Ipsita Roy Selected Research

Proteins (Proteins, Gene)

3/2020	Harmine Acts as an Indirect Inhibitor of Intracellular Protein Aggregation.
1/2019	Nucleic Acid Therapeutics in Huntington's Disease.
1/2018	Does N-terminal huntingtin function as a 'holdase' for inhibiting cellular protein aggregation?
1/2018	Designing aptamers which respond to intracellular oxidative stress and inhibit aggregation of mutant huntingtin.
1/2016	Cellular toxicity of yeast prion protein Rnq1 can be modulated by N-terminal wild type huntingtin.
12/2015	Inhibition of Aggregation of Mutant Huntingtin by Nucleic Acid Aptamers In Vitro and in a Yeast Model of Huntington's Disease.
10/2014	Effect of endogenous Hsp104 chaperone in yeast models of sporadic and familial Parkinson's disease.
6/2014	Deciphering the roles of trehalose and Hsp104 in the inhibition of aggregation of mutant huntingtin in a yeast model of Huntington's disease.
8/2013	Stabilization of bovine insulin against agitation-induced aggregation using RNA aptamers.
12/2012	Length of polyglutamine tract affects secondary and tertiary structures of huntingtin protein.

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Ipsita Roy Research Topics

Disease

13	Huntington Disease (Huntington's Disease) 03/2020 - 12/2012
6	Wounds and Injuries (Trauma) 08/2021 - 08/2006
4	Neoplasms (Cancer) 01/2022 - 04/2019
4	Neurodegenerative Diseases (Neurodegenerative Disease) 11/2021 - 10/2014
3	Proteostasis Deficiencies 03/2020 - 06/2014
3	Parkinson Disease (Parkinson's Disease) 01/2017 - 10/2014
2	Cardiovascular Diseases (Cardiovascular Disease) 01/2022 - 01/2020
2	Infections 08/2020 - 10/2013
1	Cataract (Cataracts) 01/2022
1	Breast Neoplasms (Breast Cancer) 11/2021
1	Cross Infection (Nosocomial Infection) 08/2020
1	Hemolysis 01/2020
1	Wound Infection (Wound Infections) 01/2020
1	Bacterial Infections (Bacterial Infection) 01/2020
1	Thrombosis (Thrombus) 01/2020
1	Hyperthermia 08/2019
1	Inborn Genetic Diseases (Disease, Hereditary) 01/2019
1	Mitochondrial Diseases (Mitochondrial Disease) 09/2018
1	Osteoarthritis 01/2016
1	Shock 09/2014
1	Bone Diseases (Bone Disease) 10/2013
1	Anaphylaxis (Anaphylactic Shock) 08/2013
1	Autolysis 05/2010
1	X-linked sideroblastic anemia 04/2003
1	Anemia 04/2003

Drug/Important Bio-Agent (IBA)

10	Proteins (Proteins, Gene)FDA Link 03/2020 - 12/2012
6	polyglutamineIBA 01/2020 - 12/2012
4	PolyhydroxyalkanoatesIBA 08/2021 - 08/2006
3	Pharmaceutical PreparationsIBA 11/2021 - 08/2013
3	SynucleinsIBA 01/2017 - 10/2014
2	Molecular Chaperones (Chaperone, Molecular)IBA 01/2022 - 10/2014
2	EnzymesIBA 11/2021 - 08/2019
2	PolymersIBA 01/2020 - 08/2019
2	Mutant Proteins (Protein, Mutant)IBA 01/2020 - 12/2012
2	Nucleic AcidsIBA 01/2019 - 12/2015
2	DisaccharidesIBA 06/2014 - 05/2010
2	TrehaloseIBA 06/2014 - 05/2010
1	Sirolimus (Rapamycin)FDA Link 11/2021
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 11/2021
1	Protein-Arginine DeiminasesIBA 11/2021
1	CalciumIBA 11/2021
1	N- alpha- benzoyl- N5- (2- chloro- 1- iminoethyl)- L- ornithine amideIBA 11/2021
1	beta-DefensinsIBA 08/2021
1	SilverIBA 08/2021
1	Keratins (Keratin)IBA 08/2021
1	Anti-Bacterial Agents (Antibiotics)IBA 08/2020
1	Tyr sulfate(1)- enkephalinamide-Leu (LETS)IBA 08/2020
1	Biocompatible Materials (Biomaterials)IBA 08/2020
1	HydrogelsIBA 01/2020
1	GraphiteIBA 01/2020
1	CelluloseIBA 01/2020
1	Biopolymers (Biopolymer)IBA 01/2020
1	EsterasesIBA 08/2019
1	ferric oxide (iron oxide)IBA 08/2019
1	Rifampin (Rifampicin)FDA LinkGeneric 04/2019
1	Nucleotide AptamersIBA 09/2018
1	Nicotine FDA Link 01/2017
1	PrionsIBA 01/2016
1	3-Hydroxybutyric Acid (beta-Hydroxybutyric Acid)IBA 01/2016
1	Coffee FDA Link 09/2015
1	Caffeine (No Doz)FDA LinkGeneric 09/2015
1	Amyloid (Amyloid Fibrils)IBA 10/2014
1	SaltsIBA 09/2014
1	Glycerol (Glycerine)FDA LinkGeneric 09/2014
1	Excipients (Suspending Agents)IBA 08/2013
1	TrypsinIBA 05/2010
1	Detergents (Detergent)IBA 05/2010
1	Sodium Dodecyl Sulfate (Sodium Lauryl Sulfate)IBA 05/2010
1	Sucrose (Saccharose)IBA 05/2010
1	Vitamin B 6IBA 04/2003
1	Pyridoxine (Pyridoxin)FDA LinkGeneric 04/2003
1	AcidsIBA 04/2003

Therapy/Procedure

3	Therapeutics 08/2019 - 04/2003
2	Stents 01/2020 - 11/2006
2	Sutures (Suture) 11/2006 - 08/2006
1	Microspheres (Microsphere) 11/2021
1	Diet Therapy (Therapy, Diet) 01/2016
1	Replacement Arthroplasty 01/2016
1	Tissue Scaffolds 11/2006